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#CROI 2018

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HIV: The Basics

The Road Ahead for HIV Cure Research

Today, with better understanding of the complex task at hand, cure researchers are investigating multiple avenues and taking the long view.

Will the Genetic Analysis–Based HIV Surveillance Safeguard Privacy?

The CDC is beginning to use molecular surveillance of HIV to identify transmission clusters, which has some privacy advocates concerned.

Merck’s Experimental HIV Drug Doravirine Posts Promising 96-Week Results

Compared with a regimen based on Prezista, doravirine was better for blood lipids, including cholesterol and triglycerides.

Rising PrEP Use Is Associated With Declining HIV Diagnoses in United States

This association held true even when researchers controlled for changing rates of viral suppression of HIV in 2012 to 2016 records.

Gay Men Cured of Hep C Get Reinfected at Much Higher Rate Than Drug Users

Researchers from a German cohort found that the reinfection rate for men who have sex with men was almost 10 percent per year.

Cancer Diagnosis, Treatment and Survival in People With HIV

HIV-positive people with low CD4 counts have poorer survival after a cancer diagnosis.

Isentress Doesn’t Raise Risk of “IRIS” in Those With Very Advanced HIV Disease

Immune reconstitution inflammatory syndrome (IRIS) can occur when individuals with low CD4 counts begin HIV treatment.

Treatment Rates Rise, but Adherence Does Not for Young Black Men With HIV

Certain subgroups of this population, such as smokers and those with depression, are less likely to have an undetectable viral load.

HIV Rate Among Gay & Bi Men 25 to 34 Rose 45% Between 2008 And 2015

During that time, the rate dropped 15 percent nationally and rose 25 percent among Latino men who have sex with men.

At HIV Diagnosis, Older Individuals Are More Likely to Have AIDS

This means having an AIDS-defining illness or a CD4 count below 200.
The opening session of CROI 2018 in Boston.

The Best of CROI 2018

Highlights from HIV and hepatitis C research presented at the 2018 Conference on Retroviruses and Opportunistic Infections (CROI) in Boston

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Adding Sovaldi and Ribavirin to Retreatment With Mavyret Beats Hep C

Those for whom Mavyret did not work the first time had a high cure rate with this intensified retreatment regimen.

Hepatitis C Rarely Clears Spontaneously in Those With HIV

Consequently, researchers advocate treating hep C during its early, or acute, phase among HIV-positive individuals.

Systematic Hep C Test-and-Treat Lowers Rate in Gay Men With HIV

A Swiss research program tested for and treated hep C in a large cohort of HIV-positive men who have sex with men over time.

Transmissible HIV That Is Resistant to PrEP Is Rare

An analysis of the Seattle area HIV population sought to determine the prevalence of virus resistant to both drugs in Truvada.

How HIV Alters Cells May Facilitate Sexual Transmission of Hepatitis C

A new study identifies key changes that HIV makes to Langerhans cells in the mucosal lining of the rectum.
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