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HIV-positive people have risk factors, including chronic inflammation and comorbidities, that increase the likelihood of long-term symptoms.
Latently infected cells continue to produce viral RNA and proteins, and even defective HIV can trigger persistent immune activation.
People with greater immune resilience may be at lower risk for severe COVID-19, AIDS and recurrent skin cancer, NIAID grantees find.
Poor sleep quality, sleep apnea and daytime sleepiness were linked to mood disorders and cardiovascular risk, but not to antiretrovirals.
Several mechanisms may play a role, including persistent virus and ongoing immune dysregulation.
Markers of immune activation rose, but only temporarily, around the transition to menopause.
An immune balance protocol for pre- and post-vaccination
Both HIV and autoimmune clinicians reporting lower than expected incidence
Problematic use of alcohol is likely far more common among HIV-positive people than in the general population.
Over $12 million in grants has been awarded to the Wistar Institute to research the links between opioid receptors and immune activation.
Chronic inflammation is associated with numerous harms.
Aside from taking antiretrovirals, quitting smoking is the number one way people with HIV can lower their risk of illness and death.
Proton pump inhibitors were associated with potentially harmful increased immune activation in a small study.
Researchers may have answered a bedeviling chicken-or-egg question about the persistence of HIV during antiretroviral treatment.
The Avant-Garde Awards promote research in HIV treatment and prevention in drug users.
Even when HIV is fully suppressed, such viral activity may spur persistent immune activation and complicate cure attempts.
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