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Swiss researchers analyzed shifts in kidney function among those switching from the old form of the HIV medication to the new one.
Tenofovir disoproxil fumarate is found in Truvada, Viread, Atripla, Complera and Stribild.
Italian researchers randomized half of a group of people on daily Atripla to switch to taking the single-tablet regimen every second day.
Timothy Brown may have company after a man’s virus went into remission following an HIV-resistant stem cell transplant to treat his cancer.
Delstrigo (doravirine/lamivudine/tenofovir disoproxil fumarate) includes Pifeltro (doravirine) in a three-drug single-tablet regimen.
Gilead has based its entire HIV drug portfolio on updating tenofovir, ostensibly to make it safer for bones and kidneys.
Researchers call for closer cardiovascular monitoring for those switching from the TDF form of the drug to the TAF version.
Nevertheless, researchers advise careful kidney monitoring when pairing the medications.
A large ongoing study in Botswana has found that about 1 in 150 babies exposed to Tivicay at conception developed such birth defects.
In a recent study, Edurant was better tolerated and less toxic and led to fewer discontinuations.
Various other studies have indeed found such a link.
This finding came from a larger report indicating that U.S. residents are increasingly taking drugs linked to such symptoms.
That’s compared with HIV-negative men.
Two men claim they developed bone and kidney problems after taking TDF. A related class action lawsuit has also been filed.
A new analysis finds that Gilead Sciences’ updated version of its key antiretroviral tenofovir may not actually offer any safety benefits.
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